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2008:

• Leonid Gibiansky, Parameter Estimates of Population Models: Comparison of Nonmem Versions and Estimation Methods, PAGE 17 (2008) Abstract 1268 [www.page-meeting.org/?abstract=1268], Abstract and Poster.
• Leonid Gibiansky, Ekaterina Gibiansky,Tarundeep Kakkar, Peiming Ma, Approximations of the Target-Mediated Drug Disposition Model and Identifiability of Model Parameters, PAGE 17 (2008) Abstract 1269 [www.page-meeting.org/?abstract=1269], Abstract and Poster.
• Leonid Gibiansky, Tarundeep Kakkar, Peiming Ma, Application of Identifiability Analysis Algorithm to Population PK of the Drug with Target-Mediated Drug Disposition, PAGE 17 (2008) Abstract 1271 [www.page-meeting.org/?abstract=1271], Abstract and Poster.
• Ekaterina Gibiansky, Leonid Gibiansky, Indirect Response Models with Positive Feedback: Equations, Properties, and Possible Applications, PAGE 17 (2008) Abstract 1336 [www.page-meeting.org/?abstract=1336], Abstract and Poster.
• John T. Mondick, Leonid Gibiansky, Marc R. Gastonguay, Jeffrey M. Skolnik, Michael Cole, Gareth J. Veal, Alan V. Boddy, Peter C. Adamson, and Jeffrey S. Barrett, Population Pharmacokinetic Investigation of Actinomycin-D in Children and Young Adults, Journal of Clinical Pharmacology 2008 48: 35.
• Leonid Gibiansky, Marc R. Gastonguay, Ajit Shah, Simultaneous Population Pharmacokinetic-Pharmacodynamic Modeling of Fospropofol Injection (Propofol Prodrug) and Propofol Emulsion in Healthy Volunteers, Abstract 4, American Conference on Pharmacometrics, Tucson, AZ 2008.
• William Knebel, Tim Bergsma, Jeannine Fisher, George Georgalis, Leonid Gibiansky, Bill Gillespie, Matt Riggs, and Marc R. Gastonguay, Facilitating the Pharmacometrics Work-Flow with the MItools R Package, Abstract 30, American Conference on Pharmacometrics, Tucson, AZ 2008.
• Jeannine Fisher, Marc R. Gastonguay, William Knebel, Leonid Gibiansky, Mary Beth Wire, Population Pharmacokinetic Modeling of Fosamprenavir in Pediatric HIV-Infected Patients, Abstract 48, American Conference on Pharmacometrics, Tucson, AZ 2008.

2007:

• Ajit Shah, Leonid Gibiansky, Fospropofol Intravenous Injection for Procedural Sedation: A Population Pharmacokinetic Model, 2007 Annual Meeting of American Society of Anesthesiologists.
• Leonid Gibiansky, Precision of Parameter Estimates: Covariance Step ($COV) versus Bootstrap Procedure, PAGE 16 (2007) Abstract 1106 [www.page-meeting.org/?abstract=1106]
• Matthew M. Riggs, Marc R. Gastonguay, Leonid Gibiansky, Gary Zammit, Ken Sprenger, and Lynn Aneiro, Exposure-Response Modeling of the GABAA Receptor Partial Agonist NG2-73: An Approach for Determining Target Onset and Duration of Sleep Efficacy While Minimizing Next Morning Effects, 2007 Annual Meeting of American Psychiatric Association, (page 249) Abstract NR584.
• Matthew M. Riggs, Leonid Gibiansky, Marc R. Gastonguay, Ken Sprenger, and Lynn Aneiro Exposure-Response Modeling of the GABAA Receptor Partial Agonist NG2-73, 2007 Annual Meeting, ACCP.

2006:

• Ekaterina Gibiansky, Leonid Gibiansky, Model-Based Drug Development: Optimization of AQUAVAN® Injection Dosing for Minimal-to-Moderate Sedation, PAGE 15 (2006) Abstract 959 [www.page-meeting.org/?abstract=959] .
• Leonid Gibiansky, Marc R. Gastonguay, R/NONMEM Toolbox for Simulation from Posterior Parameter (Uncertainty) Distributions, PAGE 15 (2006) Abstract 958 [www.page-meeting.org/?abstract=958]
• John T. Mondick, Leonid Gibiansky, Marc R. Gastonguay, Gareth J. Veal, Jeffrey S. Barrett, Acknowledging Parameter Uncertainty in the Simulation-Based Design of an Actinomycin-D Pharmacokinetic Study in Pediatric Patients with Wilms’ Tumor or Rhabdomyosarcoma, PAGE 15 (2006) Abstract 938 [www.page-meeting.org/?abstract=938]
• Gastonguay MR, Gibiansky L. Acknowledging and Incorporating Uncertainty in Model-Based Inferences. ECPAG Conference (2006) Workshop Poster Session, Abstract.
  
• Gastonguay MR, Gibiansky L. Acknowledging Parameter Uncertainty by Simulating from Posterior Distributions with NONMEM and R. MUFPADA Annual Meeting (2006) Abstract.

2005:

• E. Gibiansky, M. Struys, L. Gibiansky, A. Vanluchene, J. Vornov, E. Mortier, E. Burak, L. Van Bortel. AQUAVAN® Injection, a Water-Soluble Prodrug of Propofol as a Bolus Injection: A Phase I Dose Escalation Comparison with DIPRIVAN®. Part I: Pharmacokinetics. Anesthesiology. 103(4):718-729, October 2005.
• M. Struys, A. Vanluchene, E. Gibiansky, L. Gibiansky, J. Vornov, E. Mortier, L. Van Bortel. AQUAVAN® Injection, a Water-Soluble Prodrug of Propofol as a Bolus Injection: A Phase I Dose Escalation Comparison with DIPRIVAN®. Part II: Pharmacodynamics and safety. Anesthesiology. 103(4):730-743, October 2005.
• Ekaterina Gibiansky, Leonid Gibiansky, Population Pharmacokinetic-Pharmacodynamic Model of GPI 15715 and GPI-Derived Propofol in Sedation and Comparison of Models for OAA/S Scores, Abstracts of American Society of Anesthesiologists, Annual Meeting, October 22-26, 2005, Atlanta, GA
• E. Gibiansky, L. Gibiansky, and C. Wang, Model-based design of AQUAVAN® injection dose ranging Phase II study, Clinical Pharmacology & Therapeutics (2005) 79, P28–P28
• Ekaterina Gibiansky, Leonid Gibiansky, Pharmacokinetic/pharmacodynamic model of MOAA/S sedation score for GPI 15715 and GPI-derived propofol, American Society of Health-System Pharmacists Midyear Clinical Meeting and Exhibition, December 2005, Las Vegas, NE
• E. Gibiansky, L. Gibiansky. Population PK/PD model of GPI 15715 and GPI-derived propofol in sedation and comparison of PK/PD models for ordered categorical observations, PAGE 14 (2005) Abstract 735 [www.page-meeting.org/?abstract=735]
• E. Gibiansky, L. Gibiansky, J. Enriquez, Population Pharmacokinetic Model of Sedative Doses of GPI 15715 and Propofol Liberated from GPI 15715. Clinical Pharmacology & Therapeutics (2005) 77, P48–P48

2004:

• W. Bachman, L. Gibiansky Automated Evaluation of Population Pharmacokinetic and Pharmacodynamic Models, American Association of Pharmaceutical Scientists, Annual Meeting, 2004.
• E. Gibiansky; M.Struys; L. Gibiansky. Pharmacokinetics and Pharmacodynamics of AQUAVAN® bolus injection: a population PK/PD model. Eur. J. Anaesthesiology, Vol. 21, Sup. 32, 2004, p.15
• Gibiansky L. NONMEM Non-Influential Correlated ETAs Bug and How to Fix It. AAPS Annual Meeting: PPDM Poster-Podium Session, 2004.
• Farah BM, Ogola S, Anzala O, Indangasi J, Tarragona A, Gibiansky L, Bwayo J., Development and validation of gamma interferon ELISPOT assay for HIV-1 vaccine trials in Kenya. Int Conf AIDS. 2004 Jul 11-16; 15: abstract no. A10070.

2003:

• M. Gastonguay, E. Gibiansky, L. Gibiansky, and J. Barrett, Optimizing a Bayesian Dose-Adjustment Scheme for a Pediatric Trial: A Simulation Study, in Simulation for Designing Clinical Trials, A Pharmacokinetic-Pharmacodynamic Modeling Perspective (Drugs and The Pharmaceutical Sciences Series, Volume 127), Edited by H. Kimko, S. Duffull, Marcel Dekker, Inc, NY, NY 2003.
• L. Gibiansky, M. Struys, E. Gibiansky, Simultaneous Population Pharmacokinetic Model of Aquavan and Aquavan – Derived Propofol, PAGE 12 (2003) Abstract 412 [www.page-meeting.org/?abstract=412]
• E. Gibiansky, M. Struys, L. Gibiansky, Bispectral Index of Aquavan-Derived Propofol: Population PK/PD Modeling and Application to an Effect – Controlled Trial, PAGE 12 (2003) Abstract 413 [www.page-meeting.org/?abstract=413]

More than 40 publications in applied mathematics

Patents:

• E. Gibiansky, L. Gibiansky, Methods of dosing Propofol prodrugs for inducing mild to moderate levels of sedation, U.S. Application Serial No. 60/698, 404, filed on July 12, 2005
• W. Gillespie, L. Gibiansky, D. Young, S. Bigora, C. Farrell, T. Shepard, Tools for In Vitro In Vivo Correlation, submitted in 2002, Pub. Number EP1552463 (2005), US Patent 7027970 Issued on April 11, 2006.
• L. Gibiansky, Yu. Galperin, and V. Fishman, Method for optimizing net present value of a cross-selling marketing campaign, US Patent 6993493 Issued on January 31, 2006.
  
  
  

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